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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYBL2
All Species:
15.45
Human Site:
S241
Identified Species:
26.15
UniProt:
P10244
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10244
NP_002457.1
700
78764
S241
T
I
K
E
E
E
N
S
E
E
E
L
A
A
A
Chimpanzee
Pan troglodytes
XP_514658
769
86303
S241
T
I
K
E
E
E
S
S
E
E
E
L
A
A
A
Rhesus Macaque
Macaca mulatta
XP_001084853
700
78675
S241
T
I
K
E
E
E
S
S
E
E
E
P
A
A
A
Dog
Lupus familis
XP_534424
883
97262
S424
A
M
K
E
E
E
S
S
E
E
E
A
T
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P48972
704
79084
E241
V
K
E
E
S
S
E
E
E
I
A
I
A
A
T
Rat
Rattus norvegicus
NP_001100006
704
79549
E241
V
K
E
E
E
S
S
E
E
E
A
A
V
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511778
753
85883
H247
P
E
V
N
C
V
E
H
V
Q
A
S
A
F
I
Chicken
Gallus gallus
Q03237
686
77718
Q219
S
G
T
R
A
E
S
Q
T
I
V
P
N
W
P
Frog
Xenopus laevis
P52551
743
82891
T241
I
L
S
P
K
L
L
T
K
S
P
G
I
R
S
Zebra Danio
Brachydanio rerio
NP_001003867
633
70853
L200
V
D
T
T
L
H
V
L
Q
Q
T
D
T
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797351
686
76826
Q248
L
R
M
R
G
Q
G
Q
R
V
V
R
T
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P20024
340
36221
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7G7
776
86488
T245
S
E
C
S
Q
A
S
T
V
F
S
Q
S
T
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O13493
324
36522
Conservation
Percent
Protein Identity:
100
88
98.2
72.5
N.A.
85.2
87.7
N.A.
38.3
72.5
54.2
52.1
N.A.
N.A.
N.A.
N.A.
37.8
Protein Similarity:
100
89.7
98.7
74.7
N.A.
89.4
91.3
N.A.
54.5
81.5
69
65.8
N.A.
N.A.
N.A.
N.A.
54
P-Site Identity:
100
93.3
86.6
66.6
N.A.
26.6
33.3
N.A.
6.6
6.6
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
40
46.6
N.A.
13.3
20
33.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
20.1
N.A.
25.5
N.A.
20.7
Protein Similarity:
N.A.
31.8
N.A.
40.8
N.A.
29.5
P-Site Identity:
N.A.
0
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
0
N.A.
33.3
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
0
0
0
22
15
36
43
29
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
15
15
43
36
36
15
15
43
36
29
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
8
0
0
8
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
22
0
0
0
0
0
0
0
15
0
8
8
0
8
% I
% Lys:
0
15
29
0
8
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
8
0
0
8
8
8
8
0
0
0
15
0
8
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
8
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
8
15
0
0
8
% P
% Gln:
0
0
0
0
8
8
0
15
8
15
0
8
0
0
0
% Q
% Arg:
0
8
0
15
0
0
0
0
8
0
0
8
0
8
0
% R
% Ser:
15
0
8
8
8
15
43
29
0
8
8
8
8
0
8
% S
% Thr:
22
0
15
8
0
0
0
15
8
0
8
0
22
8
15
% T
% Val:
22
0
8
0
0
8
8
0
15
8
15
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _